InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DNAJA4

Summary

InnateDB Protein

IDBP-240749.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DNAJA4

Protein Name

DnaJ (Hsp40) homolog, subfamily A, member 4

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000378324

InnateDB Gene

IDBG-24554 (DNAJA4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0031072	heat shock protein binding
GO:0046872	metal ion binding
GO:0051082	unfolded protein binding
GO:0051087	chaperone binding

Biological Process

GO:0006457	protein folding
GO:0009408	response to heat
GO:0042026	protein refolding
GO:0090084	negative regulation of inclusion body assembly

Cellular Component

GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001305 Heat shock protein DnaJ, cysteine-rich domain
IPR001623 DnaJ domain
IPR002939 Chaperone DnaJ, C-terminal
IPR008971 HSP40/DnaJ peptide-binding

PFAM

PF00684
PF00226
PF01556

PRINTS

PR00625

PIRSF

SMART

SM00271

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt