Version 5.4
Mus musculus Protein: Xpo6
Summary
InnateDB Protein IDBP-622482.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpo6
Protein Name exportin 6
Synonyms 2610005L19Rik; AI854665; AL022631; C230091E20Rik; mKIAA0370; R75304; Ranbp20;
Species Mus musculus
Ensembl Protein ENSMUSP00000130527
InnateDB Gene IDBG-209411 (Xpo6)
Protein Structure
UniProt Annotation
Function Mediates the nuclear export of actin and profilin-actin complexes in somatic cells. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0008536 Ran GTPase binding
GO:0008565 protein transporter activity
Biological Process
GO:0006611 protein export from nucleus
GO:0006886 intracellular protein transport
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2429950
InterPro IPR001494 Importin-beta, N-terminal domain
IPR013598 Exportin-1/Importin-beta-like
IPR016024 Armadillo-type fold
PFAM PF03810
PF08389
PRINTS
PIRSF
SMART SM00913
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q924Z6
PhosphoSite PhosphoSite-Q924Z6
TrEMBL E9Q6V5
UniProt Splice Variant
Entrez Gene 74204
UniGene Mm.235663
RefSeq XP_006508310
MGI ID
MGI Symbol Xpo6
OMIM
CCDS
HPRD
IMGT
EMBL AC012297 AC135809 AK011324 AK154709 AY029528 BC058090
GenPept AAH58090 AAK40296 BAB27545 BAE32778

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca