InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.34208

Summary

InnateDB Protein

IDBP-692183.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.34208

Protein Name

C5a anaphylatoxin chemotactic receptor

Synonyms

C5R1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000027807

InnateDB Gene

IDBG-639986 (BT.34208)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004878	complement component C5a receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0004942	anaphylatoxin receptor activity
GO:0004944	C5a anaphylatoxin receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0030593	neutrophil chemotaxis
GO:0032494	response to peptidoglycan
GO:0038178	complement component C5a signaling pathway
GO:0042789	mRNA transcription from RNA polymerase II promoter
GO:0050679	positive regulation of epithelial cell proliferation
GO:0050830	defense response to Gram-positive bacterium
GO:0070374	positive regulation of ERK1 and ERK2 cascade

Cellular Component

GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0045177	apical part of cell

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001274 C5a1/C5a2 anaphylatoxin chemotactic receptor
IPR002234 Anaphylatoxin chemotactic receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR00426
PR01104

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite